Company Information

  

Address: 85 WELLS AVENUE
SECOND FLOOR 
City: NEWTON 
State: MA 
Zip Code: 02459 
Telephone: 617-658-0600 

Description of Business

Primary SIC Code: 2834
(As filed with the SEC)  

We are a clinical-stage pharmaceutical company focused on the discovery, development and subsequent commercialization of novel, first-in-class drugs directed against nuclear transport and related targets for the treatment of cancer and other major diseases. Our scientific expertise is focused on understanding the regulation of intracellular communication between the nucleus and the cytoplasm. We have discovered and are developing wholly-owned, novel, small molecule Selective Inhibitor of Nuclear Export, or SINE(TM), compounds that inhibit the nuclear export protein XPO1. These SINE compounds represent a new class of drug candidates with a novel mechanism of action that have the potential to treat a variety of diseases in areas of unmet medical need. Our SINE compounds were the first oral XPO1 inhibitors in clinical development.  ... More ...  

Per Share Overview

Date 12-mos Rolling EPS Dividend P/E Ratio
06/2017-3.08NAN/E
03/2017-3.28NAN/E
09/2016-3.09NAN/E
06/2016-3.26NAN/E
03/2016-3.33NAN/E
12/2015-3.32NAN/E
09/2015-3.31NAN/E
06/2015-3.06NAN/E

Key Financial Ratios and Statistics

FYE: 12/31

Profitability 2016 Leverage 2016
Net Inc/Comm Equity-0.21Total Liab/Total Assets0.10
Net Inc/Total Assets-0.61Total Liab/Inv Cap0.11
Net Inc/Inv Cap-0.67Total Liab/Comm Equity0.03
Pretax Inc/Net Sales-710.64Interest Coverage RatioNA
Net Inc/Net Sales-711.54Curr Debt/EquityNA
Cash Flow/Net Sales-547.99LTD/EquityNA
SG&A/NetSales155.51Total Debt/EquityNA
Asset Utilization   Liquidity  
Net Receivables TurnoverNAQuick Ratio7.99
Inventory TurnoverNACurrent Ratio7.99
Inventory Day SalesNANet Rec/Curr AssetsNA
Net Sales/Work Cap0.00Inv/Curr AssetsNA
Net Sales/PP&E0.05  

Income Statement (Millions)

  9/30/2017 6/30/2017 3/31/2017 12/31/2016
Total Revenues(Net Sales) 0.00 0.00 0.07 0.05
Cost of Goods Sold NA NA NA NA
Selling & Admin Exps 5.82 6.64 6.26 6.54
Operating Income -31.06 -29.75 -30.28 -27.17
Interest Exp NA NA NA 0.00
Pretax Income -30.63 -29.37 -29.89 -26.80
Other Income 0.43 0.38 0.39 0.37
Net Income Bef Extraordinary ... NA NA NA NA
Net Income -30.64 -29.39 -29.92 -26.94

Balance Sheet (Millions)

Assets 9/30/2017 6/30/2017 3/31/2017 12/31/2016
Cash & Short Term Investments 119.61 143.65 110.08 129.55
Receivables - Total NA NA NA NA
Inventories - Total NA NA NA NA
Total Current Assets 121.68 145.72 112.23 131.64
Net Property, Plant & Equipment 2.30 2.47 2.65 2.84
Total Assets 163.77 185.75 155.44 180.39
Liabilities        
Accounts Payable 19.61 16.12 14.99 16.11
Debt in Current Liabilities NA NA NA NA
Total Current Liabilities 21.16 17.52 15.48 16.48
Long-Term Debt NA NA NA NA
Total Liabilities 22.60 19.04 17.07 18.14
Stockholder's Equity        
Minority Interest NA NA NA NA
Preferred Stock 0.00 0.00 0.00 0.00
Common Stock 0.01 0.01 0.00 0.00
Retained Earnings -456.30 -425.66 -396.28 -366.10
Treasury Stock NA NA NA NA
Total Stockholders' Equity 141.18 166.71 138.36 162.24
Total Liabilities and Stockholders' Equity 163.77 185.75 155.44 180.39

Cash Flow Summary (Millions)

Categories 9/30/2017 6/30/2017 3/31/2017 12/31/2016
Net Cash Provided by Operating Activities -21.75 -21.72 -24.71 -20.00
Net Cash Provided by Investing Activities 20.59 -1.13 0.55 6.60
Net Cash Provided by Financing Activities 0.16 52.57 0.06 19.25

Annual Summary Data (Millions)

Year Sales Net Income EPS
12/20120.63-15.89--
12/20130.39-33.95-5.59
12/20140.23-75.78-2.43
12/20150.25-118.18-3.32
12/20160.15-109.58--
Growth Rates-29.80----

Stock Ownership

Type Date(Q,M) No. Owners Shares Held (000s) % Own
Institutional09/30/178428,75660.95




Report Date : 12/11/2017

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